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Comparison of Plasmodium ovale curtisi and Plasmodium ovale wallikeri infections by a meta-analysis approach

March 24, 2021 - 14:16 -- Open Access
Mahittikorn A, Masangkay FR, Kotepui KU, Milanez GJ, Kotepui M
Sci Rep. 2021 Mar 19;11(1):6409

Malaria caused by Plasmodium ovale species is considered a neglected tropical disease with limited information about its characteristics. It also remains unclear whether the two distinct species P. ovale curtisi and P. ovale wallikeri exhibit differences in their prevalence, geographic distribution, clinical characteristics, or laboratory parameters. Therefore, this study was conducted to clarify these differences to support global malaria control and eradication programs. Studies reporting the occurrence of P. ovale curtisi and P. ovale wallikeri were explored in databases.

Plasmodium ovale wallikeri and P. ovale curtisi Infections and Diagnostic Approaches to Imported Malaria, France, 2013-2018

February 3, 2021 - 14:07 -- Open Access
Joste V, Bailly J, Hubert V, Pauc C, Gendrot M, Guillochon E, Madamet M, Thellier M, Kendjo E, Argy N, Pradines B, Houzé S
Emerg Infect Dis. 2021 Feb;27(2)

We retrospectively analyzed epidemiologic, clinical, and biologic characteristics of 368 Plasmodium ovale wallikeri and 309 P. ovale curtisi infections treated in France during January 2013–December 2018. P. ovale wallikeri infections displayed deeper thrombocytopenia and shorter latency periods. Despite similar clinical manifestations, P. ovale wallikeri–infected patients were more frequently treated with artemisinin-based combination therapy.

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