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Heterogeneity in response to serological exposure markers of recent Plasmodium vivax infections in contrasting epidemiological contexts

February 17, 2021 - 09:21 -- Open Access
Rosado J, White MT, Mueller I, et al.
PLoS Negl Trop Dis. 2021 Feb 16;15(2):e0009165

Antibody responses as serological markers of Plasmodium vivax infection have been shown to correlate with exposure, but little is known about the other factors that affect antibody responses in naturally infected people from endemic settings. To address this question, we studied IgG responses to novel serological exposure markers (SEMs) of P. vivax in three settings with different transmission intensity.

The causes of holes and loss of physical integrity in long‐lasting insecticidal nets

January 20, 2021 - 08:30 -- Open Access
Amy Wheldrake, Estelle Guillemois, Hamidreza Arouni, Vera Chetty and Stephen J. Russell
Malaria Journal 2021 20:45, 19 January 2021

Long-lasting insecticidal nets (LLINs) are expected to last for at least 3 years, but whilst this may be achieved from an insecticidal perspective, physical protection is frequently compromised much earlier because of the rapid accumulation of holes during use. To understand why LLINs are so susceptible to loss of physical integrity, thousands of hole damage sites in LLINs retrieved from the field in Africa and Asia were forensically studied to identify the persistent underlying causes.

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