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dihydro-artemisinin-piperaquine

Understanding adherence to reactive treatment of asymptomatic malaria infections in The Gambia

January 20, 2021 - 07:08 -- Open Access
Author(s): 
Jaiteh F, Okebe J, Masunaga Y, D'Alessandro U, Achan J, Gryseels C, de Vries D, Ribera JM, Grietens KP
Reference: 
Sci Rep. 2021 Jan 18;11(1):1746

The impact of different types of reactive case detection and/or treatment strategies for malaria elimination depends on high coverage and participants' adherence. However, strategies to optimise adherence are limited, particularly for people with asymptomatic or no infections. As part of a cluster-randomized trial to evaluate the effect of reactive treatment in The Gambia, all residents in the compound of a diagnosed clinical malaria patient received dihydro-artemisinin-piperaquine (DP). Using a mixed method approach, we assessed which factors contribute to adherence among the contacts of malaria cases that showed no symptoms.

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