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Systematic review

A systematic review assessing the potential for release of vector species from competition following insecticide-based population suppression of Anopheles species in Africa

September 14, 2021 - 09:17 -- Open Access
Qureshi A, Connolly JB
Parasit Vectors. 2021 Sep 8;14(1):462

While insecticide-based vector control can effectively target vector species in areas of high malaria endemicity, such as Anopheles gambiae in Africa, residual disease transmission can occur. Understanding the potential role of competitive displacement between vector species could inform both current insecticide-based vector control programmes and the development of future complementary interventions.

A Systematic Review of the Evidence on the Effectiveness and Cost-Effectiveness of Mass Screen-and-Treat Interventions for Malaria Control

September 8, 2021 - 16:57 -- Open Access
Kim S, Luande VN, Rocklöv J, Carlton JM, Tozan Y
Am J Trop Med Hyg. 2021 Sep 7:tpmd210325

Malaria elimination and eradication efforts have stalled globally. Further, asymptomatic infections as silent transmission reservoirs are considered a major challenge to malaria elimination efforts. There is increased interest in a mass screen-and-treat (MSAT) strategy as an alternative to mass drug administration to reduce malaria burden and transmission in endemic settings.

Effectiveness of spatially targeted interventions for control of HIV, tuberculosis, leprosy and malaria: a systematic review

July 20, 2021 - 13:22 -- Open Access
Khundi M, Carpenter JR, Nliwasa M, Cohen T, Corbett EL, MacPherson P
BMJ Open. 2021 Jul 13;11(7):e044715

As infectious diseases approach global elimination targets, spatial targeting is increasingly important to identify community hotspots of transmission and effectively target interventions. We aimed to synthesise relevant evidence to define best practice approaches and identify policy and research gaps.

The application of spectroscopy techniques for diagnosis of malaria parasites and arboviruses and surveillance of mosquito vectors: A systematic review and critical appraisal of evidence

April 28, 2021 - 14:29 -- Open Access
Goh B, Ching K, Soares Magalhães RJ, Ciocchetta S, Edstein MD, Maciel-de-Freitas R, Sikulu-Lord MT
PLoS Negl Trop Dis. 2021 Apr 22;15(4):e0009218

The potential of RS as a surveillance tool for malaria and arbovirus vectors and MIRS for the diagnosis and surveillance of arboviruses is yet to be assessed. NIRS capacity as a surveillance tool for malaria and arbovirus vectors should be validated under field conditions, and its potential as a diagnostic tool for malaria and arboviruses needs to be evaluated.

NOT Open Access | Epidemiology of malaria among HIV/AIDS patients in sub-Saharan Africa: A systematic review and meta-analysis of observational studies

March 2, 2021 - 15:42 -- NOT Open Access
Obebe OO, Falohun OO
Acta Trop. 2021 Mar;215:105798

Malaria related HIV morbidity and death is a concern in sub-Saharan Africa. Understanding the epidemiology of malaria among people living with HIV is vital for adequate intervention. We conducted a systematic review and meta-analysis to estimate the prevalence of malaria in HIV patients in sub-Saharan Africa. We searched PubMed, AJOL, Web of Science and Google Scholar databases.

Endectocides as a complementary intervention in the malaria control program: a systematic review

January 20, 2021 - 07:25 -- Open Access
Khaligh FG, Jafari A, Silivanova E, Levchenko M, Rahimi B, Gholizadeh S
Syst Rev. 2021 Jan 18;10(1):30

Malaria is the most common vector-borne disease transmitted to humans by Anopheles mosquitoes. Endectocides and especially ivermectin will be available as a vector control tool soon. The current review could be valuable for trial design and clinical studies to control malaria transmission.

Systematic review of registered trials of Hydroxychloroquine prophylaxis for COVID-19 health-care workers at the first third of 2020

December 2, 2020 - 09:55 -- Open Access
Bienvenu AL, Marty AM, Jones MK, Picot S
One Health. 2020 Dec;10:100141

In the absence of a vaccine the medical and scientific community is looking intensely at utilizing a pre or post exposure drug that could decrease viremia. The search for a medication that could reduce risk of serious disease, and ideally of any manifestation of disease from SARS-CoV2, and of asymptomatic shedding of SARS-CoV2 is of urgent interest. Repurposing existing pharmaceuticals is among the approaches to achieve these ends.

The association of malaria infection and gestational hypertension in Africa: Systematic review and meta-analysis

December 2, 2020 - 08:32 -- Open Access
Mruma HA, McQuillan R, Norrie J
J Glob Health. 2020 Dec;10(2):020417

The World Health Organisation (WHO) estimates that hypertensive disorders of pregnancy (HDP) contribute 14% to global maternal mortality. HDP encompasses several subcategories, including gestational hypertension (GH) and pre-eclampsia. These two conditions are both characterised by a rise in blood pressure, with an onset from 20 weeks of gestation. They also share some common risk factors. The current definition of pre-eclampsia includes raised blood pressure in the absence of proteinuria, thus presenting the two conditions as a spectrum. In this article, we refer to both conditions as gestational hypertension, which is our outcome of interest. The aetiology of GH is not yet clearly understood. Observational studies have suggested that malaria may be associated with GH. However, the evidence from these small studies has been inconclusive. Having a better understanding of the association between malaria and GH may help inform prevention strategies to reduce maternal and infant mortality and morbidity.

The impact of delayed treatment of uncomplicated P. falciparum malaria on progression to severe malaria: A systematic review and a pooled multicentre individual-patient meta-analysis

October 21, 2020 - 08:39 -- Open Access
Mousa A, Al-Taiar A, Okell LC, et al.
PLoS Med. 2020 Oct 19;17(10):e1003359

Delay in receiving treatment for uncomplicated malaria (UM) is often reported to increase the risk of developing severe malaria (SM), but access to treatment remains low in most high-burden areas. Understanding the contribution of treatment delay on progression to severe disease is critical to determine how quickly patients need to receive treatment and to quantify the impact of widely implemented treatment interventions, such as ‘test-and-treat’ policies administered by community health workers (CHWs). We conducted a pooled individual-participant meta-analysis to estimate the association between treatment delay and presenting with SM.

Prevalence of and risk factors for Plasmodium spp. co-infection with hepatitis B virus: a systematic review and meta-analysis

October 15, 2020 - 08:46 -- Open Access
Kwuntida Uthaisar Kotepui and Manas Kotepui
Malaria Journal 2020 19:368, 15 October 2020

Plasmodium spp. and hepatitis B virus (HBV) are among the most common infectious diseases in underdeveloped countries. This study aimed to determine the prevalence of Plasmodium spp. and HBV co-infection in people living in endemic areas of both diseases and to assess the risk factors related to this co-infection.


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