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NOT Open Access | Erythrocyte Binding Activity of PkDBPalphaII of Plasmodium knowlesi Isolated from High and Low Parasitemia Cases

December 16, 2020 - 10:53 -- NOT Open Access
Mohd Bukhari FD, Lau YL, Fong MY
Am J Trop Med Hyg. 2020 Dec 14

Invasion of Plasmodium knowlesi merozoite into human erythrocytes involves molecular interaction between the parasite's Duffy binding protein (PkDBPαII) and the Duffy antigen receptor for chemokines on the erythrocytes. This study investigates the binding activity of human erythrocyte with PkDBPαII of P. knowlesi isolates from high and low parasitemic patients in an erythrocyte binding assay.

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