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The malaria parasite sheddase SUB2 governs host red blood cell membrane sealing at invasion

December 9, 2020 - 07:45 -- Open Access
Author(s): 
Collins CR, Hackett F, Howell SA, Snijders AP, Russell MR, Collinson LM, Blackman MJ
Reference: 
Elife. 2020 Dec 8;9:e61121

Red blood cell (RBC) invasion by malaria merozoites involves formation of a parasitophorous vacuole into which the parasite moves. The vacuole membrane seals and pinches off behind the parasite through an unknown mechanism, enclosing the parasite within the RBC.

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