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interferon lambda

B cell intrinsic expression of IFNlambda receptor suppresses the acute humoral immune response to experimental blood-stage malaria

December 2, 2020 - 09:49 -- Open Access
Author(s): 
Hahn WO, Pepper M, Liles WC
Reference: 
Virulence. 2020 Dec;11(1):594-606

Antibodies play a critical protective role in the host response to blood-stage malaria infection. The role of cytokines in shaping the antibody response to blood-stage malaria is unclear. Interferon lambda (IFNλ), a type III interferon, is a cytokine produced early during blood-stage malaria infection that has an unknown physiological role during malaria infection.

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