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SARS-COV2 and P. falciparum common immunodominant regions may explain low COVID-19 incidence in the malaria-endemic belt

November 25, 2020 - 12:39 -- Open Access
Iesa MA, Osman ME, Hassan MA, Dirar AI, Abuzeid N, Mancuso JJ, Pandey R, Mohammed AA, Borad MJ, Babiker HM, Konozy EH
New Microbes New Infect. 2020 Nov 19:100817

COVID-19 has caused significant morbidity and mortality, and new cases are on the rise globally, yet malaria-endemic areas report statistically significant lower incidences. We identified potential shared targets for an immune response to SARS-CoV-2 by immune determinants shared identities with Plasmodium falciparum using IEDB's Immune browser tool 9.0.

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