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plasmodial kinase inhibitors

An Update on Development of Small-Molecule Plasmodial Kinase Inhibitors

November 11, 2020 - 14:13 -- Open Access
Author(s): 
Moolman C, Sluis RV, Beteck RM, Legoabe LJ
Reference: 
Molecules. 2020 Nov 7;25(21):E518

Malaria control relies heavily on the small number of existing antimalarial drugs. However, recurring antimalarial drug resistance necessitates the continual generation of new antimalarial drugs with novel modes of action. In order to shift the focus from only controlling this disease towards elimination and eradication, next-generation antimalarial agents need to address the gaps in the malaria drug arsenal.

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