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RNASE 3 polymorphisms

Haplotype of RNASE 3 polymorphisms is associated with severe malaria in an Indian population

October 31, 2020 - 09:53 -- Open Access
Author(s): 
Mukhi B, Gupta H, Wassmer SC, Anvikar AR, Ghosh SK
Reference: 
Mol Biol Rep. 2020 Oct 28

Severe malaria (SM) caused by Plasmodium falciparum (Pf) infection has been associated with life-threatening anemia, metabolic acidosis, cerebral malaria and multiorgan dysfunction. It may lead to death if not treated promptly. RNASE 3 has been linked to Pf growth inhibition and its polymorphisms found associated with SM and cerebral malaria in African populations.

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