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bryozoan amathia

NOT Open Access | Antiplasmodial Alkaloids from the Australian Bryozoan Amathia lamourouxi

October 28, 2020 - 09:55 -- NOT Open Access
Kleks G, Holland DC, Kennedy EK, Avery VM, Carroll AR
J Nat Prod. 2020 Oct 26

An extract from the bryozoan Amathia lamourouxi with antiplasmodial activity was identified through high-throughput screening of an Australian marine invertebrate extract library against Plasmodium falciparum. Chemical investigation of A. lamourouxi resulted in the isolation of six new brominated alkaloids, convolutamines K and L (1 and 2), volutamides F-H (3-5), and 2,5-dibromo-1-methyl-1H-indole-3-carbaldehyde (6).

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