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prophylaxis treatment

Hydroxychloroquine prophylaxis and treatment is ineffective in macaque and hamster SARS-CoV-2 disease models

October 27, 2020 - 15:46 -- Open Access
Author(s): 
Rosenke K, Jarvis MA, Feldmann H, et al.
Reference: 
JCI Insight. 2020 Oct 22:143174

We remain largely without effective prophylactic/therapeutic interventions for COVID-19. Although many human COVID-19 clinical trials are ongoing, there remains a deficiency of supportive preclinical drug efficacy studies to help guide decisions. Here we assessed the prophylactic/therapeutic efficacy of hydroxychloroquine (HCQ), a drug of interest for COVID-19 management, in two animal disease models.

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