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oral administration

NOT Open Access | Identification and Pharmacokinetics of Quinone Reductase 2 Inhibitors after Oral Administration of Garcinia mangostana L. Extract in Rat by LC-MS/MS

October 20, 2020 - 16:02 -- NOT Open Access
Author(s): 
Liang X, Hu Y, Li J, Chang AK, Tao X, Li Y, Liu W, Pi K, Yuan J, Jiang Z
Reference: 
J Agric Food Chem. 2020 Oct 15

Garcinia mangostana L. (mangosteen) is a famous tropical fruit that contains a large number of xanthones. Regular consumption of mangosteen may confer health benefits and prevent some diseases, such as malaria. Quinone reductase 2 (QR-2) is a cytosolic enzyme found in human red blood cells, and it is becoming a target for chemoprevention because it is involved in the mechanisms of several diseases, including malaria.

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