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host cell-directed

The contribution of host cell-directed vs. parasite-directed immunity to the disease and dynamics of malaria infections

November 5, 2019 - 12:47 -- Open Access
Nina Wale, Matthew J. Jones, Derek G. Sim, Andrew F. Read, and Aaron A. King
PNAS October 29, 2019 116 (44) 22386-22392

Hosts defend themselves against pathogens by mounting an immune response. Fully understanding the immune response as a driver of host disease and pathogen evolution requires a quantitative account of its impact on parasite population dynamics.

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