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2-hydroxyethyl 2-bromoisobutyrate

Rapid quantification of the malaria biomarker hemozoin by improved biocatalytically initiated precipitation atom transfer radical polymerizations

October 7, 2020 - 14:35 -- Open Access
Raccio S, Pollard J, Djuhadi A, Balog S, Pellizzoni MM, Rodriguez KJ, Rifaie-Graham O, Bruns N
Analyst. 2020 Oct 1

The fight against tropical diseases such as malaria requires the development of innovative biosensing techniques. Diagnostics must be rapid and robust to ensure prompt case management and to avoid further transmission. The malaria biomarker hemozoin can catalyze atom transfer radical polymerizations (ATRP), which we exploit in a polymerization-amplified biosensing assay for hemozoin based on the precipitation polymerization of N-isopropyl acrylamide (NIPAAm).

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