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antibacterial therapy

Time for pragmatic, prospective clinical trials to determine the role of empirical antibacterial therapy in critically ill adults hospitalised with malaria

October 6, 2020 - 12:56 -- Open Access
Author(s): 
Hanson J, Nyein PP, Aung NM, Kyi MM
Reference: 
Int J Infect Dis. 2020 Oct 2:S1201-9712(20)32188-3

Children with severe falciparum malaria in malaria-endemic regions are predisposed to developing life-threatening bacterial co-infection. International guidelines therefore recommend empirical broad-spectrum antibacterial therapy in these children. Few studies have examined co-infection in adults, although it has been believed to be relatively rare; anti-bacterial therapy is therefore not routinely recommended in adults.

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