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transmission blocking drugs

Natural Products: A Potential Source of Malaria Transmission Blocking Drugs

September 23, 2020 - 09:00 -- Open Access
Author(s): 
Moyo P, Mugumbate G, Eloff JN, Louw AI, Maharaj VJ, Birkholtz LM
Reference: 
Pharmaceuticals (Basel). 2020 Sep 17;13(9):E251

The ability to block human-to-mosquito and mosquito-to-human transmission of Plasmodium parasites is fundamental to accomplish the ambitious goal of malaria elimination. The WHO currently recommends only primaquine as a transmission-blocking drug but its use is severely restricted by toxicity in some populations. New, safe and clinically effective transmission-blocking drugs therefore need to be discovered.

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