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Latin America

The clinical–epidemiological profile of malaria patients from Southern Venezuela, a critical hotspot in Latin America

October 6, 2021 - 20:07 -- Open Access
David A. Forero-Peña, Fhabián S. Carrión-Nessi, Ananías A. Escalante, et al.
Malaria Journal 2021 20:375, 20 September 2021

Venezuela accounted for 55% of the cases and 73% of the malaria deaths in the Americas in 2019. Bolivar state, in the southeast, contributes > 60% of the country's Plasmodium vivax and Plasmodium falciparum cases every year. This study describes the clinical–epidemiological characteristics of clinical malaria patients in this high-transmission area.

Malaria in Southern Venezuela: The hottest hotspot in Latin America

January 27, 2021 - 10:49 -- Open Access
Grillet ME, Moreno JE, Hernández-Villena JV, Vincenti-González MF, Noya O, Tami A, Paniz-Mondolfi A, Llewellyn M, Lowe R, Escalante AA, Conn JE
PLoS Negl Trop Dis. 2021 Jan 25;15(1):e0008211

Malaria elimination in Latin America is becoming an elusive goal. Malaria cases reached a historical ~1 million in 2017 and 2018, with Venezuela contributing 53% and 51% of those cases, respectively. Historically, malaria incidence in southern Venezuela has accounted for most of the country's total number of cases. The efficient deployment of disease prevention measures and prediction of disease spread to new regions requires an in-depth understanding of spatial heterogeneity on malaria transmission dynamics. Herein, we characterized the spatial epidemiology of malaria in southern Venezuela from 2007 through 2017 and described the extent to which malaria distribution has changed country-wide over the recent years.

House modifications for preventing malaria

October 20, 2020 - 16:15 -- Open Access
Furnival-Adams J, Olanga EA, Napier M, Garner P
Cochrane Database Syst Rev. 2020 Oct 15;10:CD013398

Despite being preventable, malaria remains an important public health problem. The World Health Organization (WHO) reports that overall progress in malaria control has plateaued for the first time since the turn of the century. Researchers and policymakers are therefore exploring alternative and supplementary malaria vector control tools. Research in 1900 indicated that modification of houses may be effective in reducing malaria: this is now being revisited, with new research now examining blocking house mosquito entry points or modifying house construction materials to reduce exposure of inhabitants to infectious bites.

When fever is not malaria in Latin America: a systematic review

September 23, 2020 - 08:48 -- Open Access
Moreira J, Barros J, Lapouble O, Lacerda MVG, Felger I, Brasil P, Dittrich S, Siqueira AM
BMC Med. 2020 Sep 21;18(1):294

In malaria-endemic countries, febrile episodes caused by diseases other than malaria are a growing concern. However, limited knowledge of the prevalent etiologic agents and their geographic distributions restrict the ability of health services to address non-malarial morbidity and mortality through effective case management. Here, we review the etiology of fever in Latin America (LA) between 1980 and 2015 and map significant pathogens commonly implicated in febrile infectious diseases.

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