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NOT Open Access | Ape Origins of Human Malaria

September 10, 2020 - 14:23 -- NOT Open Access
Author(s): 
Sharp PM, Plenderleith LJ, Hahn BH
Reference: 
Annu Rev Microbiol. 2020 Sep 8;74:39-63

African apes harbor at least twelve Plasmodium species, some of which have been a source of human infection. It is now well established that Plasmodium falciparum emerged following the transmission of a gorilla parasite, perhaps within the last 10,000 years, while Plasmodium vivax emerged earlier from a parasite lineage that infected humans and apes in Africa before the Duffy-negative mutation eliminated the parasite from humans there.

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