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Plasmodium falciparum life cycle

A Novel Tool for the Generation of Conditional Knockouts To Study Gene Function across the Plasmodium falciparum Life Cycle

November 5, 2019 - 12:43 -- Open Access
Marta Tibúrcio, Annie S. P. Yang, Moritz Treeck, et al.
mBio September/October 2019 10:e01170-19

Plasmodium falciparum has a complex life cycle that involves interaction with multiple tissues inside the human and mosquito hosts. Identification of essential genes at all different stages of the P. falciparum life cycle is urgently required for clinical development of tools for malaria control and eradication.

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Genetic mapping of fitness determinants across the malaria parasite Plasmodium falciparum life cycle

October 28, 2019 - 16:20 -- Open Access
Xue Li, Sudhir Kumar, Ashley M. Vaughan, et al.
PLoS Genet 15(10): e1008453

Determining the genetic basis of fitness is central to understanding evolution and transmission of microbial pathogens.

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