The world's scientific and social network for malaria professionals
Subscribe to free Newsletter | 10735 malaria professionals are enjoying the free benefits of MalariaWorld today

host decoy traps

Plasmodium falciparum gametocyte-induced volatiles enhance attraction of Anopheles mosquitoes in the field

September 8, 2020 - 11:54 -- Open Access
Author(s): 
Yared Debebe, Sharon Rose Hill, Göran Birgersson, Habte Tekie and Rickard Ignell
Reference: 
Malaria Journal 2020 19:327, 4 September 2020

Plasmodium parasites manipulate the interaction between their mosquito and human hosts. Patients infected with gametocytes attract anopheline mosquitoes differentially compared to healthy individuals, an effect associated with an increased release of attractive volatile cues. This odour-driven manipulation is partly mediated by the gametocyte-specific metabolite, (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate (HMBPP), which induces increased release of select aldehydes and terpenes from red blood cells and results in the enhanced attraction of host-seeking mosquitoes, which are vectors of malaria. This study investigates the effect of the HMBPP-induced volatiles on the attraction of wild Anopheles mosquitoes to humans under field conditions.

Subscribe to RSS - host decoy traps