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DRC

NOT Open Access | What is the burden of malaria in the DRC

October 20, 2020 - 16:09 -- NOT Open Access
Author(s): 
Deutsch-Feldman M, Parr JB, Keeler C, Brazeau NF, Goel V, Emch M, Edwards JK, Kashamuka M, Tshefu AK, Meshnick SR
Reference: 
J Infect Dis. 2020 Oct 15:jiaa650

Despite evidence that older children and adolescents bear the highest burden of malaria, large malaria surveys focus on younger children.

How useful are malaria risk maps at the country level? Perceptions of decision-makers in Kenya, Malawi and the Democratic Republic of Congo

October 6, 2020 - 12:47 -- Open Access
Author(s): 
Ludovica Ghilardi, George Okello, Jayne Webster, et al.
Reference: 
Malaria Journal 2020 19:353, 2 October 2020

Declining malaria prevalence and pressure on external funding have increased the need for efficiency in malaria control in sub-Saharan Africa (SSA). Modelled Plasmodium falciparum parasite rate (PfPR) maps are increasingly becoming available and provide information on the epidemiological situation of countries. However, how these maps are understood or used for national malaria planning is rarely explored. In this study, the practices and perceptions of national decision-makers on the utility of malaria risk maps, showing prevalence of parasitaemia or incidence of illness, was investigated.

The lack of K13-propeller mutations associated with artemisinin resistance in Plasmodium falciparum in Democratic Republic of Congo (DRC)

August 25, 2020 - 07:55 -- Open Access
Author(s): 
Yobi DM, Kayiba NK, Mvumbi DM, Boreux R, Bontems S, Kabututu PZ, De Mol P, Speybroeck N, Mvumbi GL, Hayette MP
Reference: 
PLoS One. 2020 Aug 21;15(8):e0237791

Artemisinin-based combination therapies (ACTs) have been recommended by the World Health Organization (WHO) as first-line treatment of uncomplicated Plasmodium falciparum (P. falciparum) malaria since 2005 in Democratic Republic of Congo (DRC) and a regular surveillance of the ACT efficacy is required to ensure the treatment effectiveness. Mutations in the propeller domain of the pfk13 gene were identified as molecular markers of artemisinin resistance (ART-R).

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