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surface-active ionic liquids

Building on Surface-Active Ionic Liquids for the Rescuing of the Antimalarial Drug Chloroquine

July 30, 2020 - 14:00 -- Open Access
Silva AT, Lobo L, Oliveira IS, Gomes J, Teixeira C, Nogueira F, Marques EF, Ferraz R, Gomes P
Int J Mol Sci. 2020 Jul 27;21(15):E5334

Ionic liquids derived from classical antimalarials are emerging as a new approach towards the cost-effective rescuing of those drugs. Herein, we disclose novel surface-active ionic liquids derived from chloroquine and natural fatty acids whose antimalarial activity in vitro was found to be superior to that of the parent drug.

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