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febrile malaria

Microscopic and sub-microscopic asymptomatic Plasmodium falciparum infections in Ghanaian children and protection against febrile malaria

July 28, 2020 - 14:46 -- Open Access
Author(s): 
Adu B, Issahaque QA, Sarkodie-Addo T, Kumordjie S, Kyei-Baafour E, Sinclear CK, Eyia-Ampah S, Owusu-Yeboa E, Theisen M, Dodoo D
Reference: 
Infect Immun. 2020 Jul 27:IAI.00125-20

Naturally acquired immunity to Plasmodium falciparum malaria is thought to be non-sterile and sustained by persistence of low level parasitaemia. This study assessed the association between baseline microscopic and submicroscopic asymptomatic P. falciparum infections and anti-malarial antibody levels and whether these parasitaemia modify protective associations between antibody levels and malaria in Ghanaian children.

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