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peptide-based vaccine candidates

NOT Open Access | Designing peptide-based vaccine candidates for Plasmodium falciparum erythrocyte binding antigen 175

July 28, 2020 - 14:44 -- NOT Open Access
Author(s): 
Chauhan S, Kumar R, Khan N, Verma S, Sehgal R, Tripathi PK, Farooq U
Reference: 
Biologicals. 2020 Jul 24:S1045-1056(20)30078-6

Plasmodium falciparum leads to a virulent form of malaria. Progress has been achieved in understanding the mechanisms involved in the malarial infection, still there is no effective vaccine to prevent severe infection. An effective vaccine against malaria should be one which can induce immune responses against multiple epitopes in the context of predominantly occurring HLA alleles.

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