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Use of a highly specific kinase inhibitor for rapid, simple and precise synchronization of Plasmodium falciparum and Plasmodium knowlesi asexual blood-stage parasites

July 20, 2020 - 15:15 -- Open Access
Ressurreição M, Thomas JA, Nofal SD, Flueck C, Moon RW, Baker DA, van Ooij C.
PLoS ONE 15(7): e0235798

During the course of the asexual erythrocytic stage of development, Plasmodium spp. parasites undergo a series of morphological changes and induce alterations in the host cell. At the end of this stage, the parasites egress from the infected cell, after which the progeny invade a new host cell. These processes are rapid and occur in a time-dependent manner.

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