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sequencing platforms

Inversion Genotyping in the Anopheles gambiae Complex Using High-Throughput Array and Sequencing Platforms

July 20, 2020 - 16:05 -- Open Access
Author(s): 
Love RR, Pombi M, Guelbeogo MW, Campbell NR, Stephens MT, Dabire RK, Costantini C, Torre AD, Besansky NJ
Reference: 
G3 (Bethesda). 2020 Jul 17:g3.401418.2020.

Chromosomal inversion polymorphisms have special importance in the Anopheles gambiae complex of malaria vector mosquitoes, due to their role in local adaptation and range expansion. The study of inversions in natural populations is reliant on polytene chromosome analysis by expert cytogeneticists, a process that is limited by the rarity of trained specialists, low throughput, and restrictive sampling requirements.

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