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ICAM-1 binding

Structural insights into diverse modes of ICAM-1 binding by Plasmodium falciparum-infected erythrocytes

October 8, 2019 - 15:36 -- Open Access
Frank Lennartz, Cameron Smith, Alister G. Craig, and Matthew K. Higgins
PNAS October 1, 2019 116 (40) 20124-20134

A major determinant of pathogenicity in malaria caused by Plasmodium falciparum is the adhesion of parasite-infected erythrocytes to the vasculature or tissues of infected individuals.

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