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plasmodium ovale wallikeri

Polymorphism analysis of propeller domain of k13 gene in Plasmodium ovale curtisi and Plasmodium ovale wallikeri isolates original infection from Myanmar and Africa in Yunnan Province, China

July 14, 2020 - 09:40 -- Open Access
Author(s): 
Mengni Chen, Ying Dong, Yan Deng, Yanchun Xu, Yan Liu, Canglin Zhang and Herong Huang
Reference: 
Malaria Journal 2020 19:246, 13 July 2020

Eighteen imported ovale malaria cases imported from Myanmar and various African countries have been reported in Yunnan Province, China from 2013 to 2018. All of them have been confirmed by morphological examination and 18S small subunit ribosomal RNA gene (18S rRNA) based PCR in YNRL. Nevertheless, the subtypes of Plasmodium ovale could not be identified based on 18S rRNA gene test, thus posing challenges on its accurate diagnosis. To help establish a more sensitive and specific method for the detection of P. ovale genes, this study performs sequence analysis on k13-propeller polymorphisms in P. ovale.

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