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pfcsp gene

Genetic polymorphism of Plasmodium falciparum circumsporozoite protein on Bioko Island, Equatorial Guinea and global comparative analysis

July 14, 2020 - 09:34 -- Open Access
Author(s): 
Hui-Ying Huang, Xue-Yan Liang, Min Lin, et al.
Reference: 
Malaria Journal 2020 19:245, 13 July 2020

Plasmodium falciparum circumsporozoite protein (PfCSP) is a potential malaria vaccine candidate, but various polymorphisms of the pfcsp gene among global P. falciparum population become the major barrier to the effectiveness of vaccines. This study aimed to investigate the genetic polymorphisms and natural selection of pfcsp in Bioko and the comparison among global P. falciparum population.

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