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Adaptive immune responses mediated age-related Plasmodium yoelii 17XL and 17XNL infections in 4 and 8-week-old BALB/c mice

January 12, 2021 - 15:10 -- Open Access
Author(s): 
Wang QB, Du YT, Liu F, Sun XD, Sun X, Chen G, Pang W, Cao YM
Reference: 
BMC Immunol. 2021 Jan 11;22(1):6

It is important to expound the opposite clinical outcomes between children and adulthood for eradicate malaria. There remains unknown about the correlation between adaptive immune response and age-related in malaria.

Impact of Four Rounds of Mass Drug Administration with Dihydroartemisinin-Piperaquine Implemented in Southern Province, Zambia

July 6, 2020 - 17:08 -- Open Access
Author(s): 
Eisele TP, Bennett A, Miller JM, et al.
Reference: 
Am J Trop Med Hyg. 2020 Jul 2

Over the past decade, Zambia has made substantial progress against malaria and has recently set the ambitious goal of eliminating by 2021. In the context of very high vector control and improved access to malaria diagnosis and treatment in Southern Province, we implemented a community-randomized controlled trial to assess the impact of four rounds of community-wide mass drug administration (MDA) and household-level MDA (focal MDA) with dihydroartemisinin-piperaquine (DHAP) implemented between December 2014 and February 2016.

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