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plasmodium ovale spp.

Epidemiological profile of Plasmodium ovale spp. imported from Africa to Anhui Province, China, 2012–2019

January 9, 2021 - 12:22 -- Open Access
Tao Zhang, Shuqi Wang, Weidong Li, et al.
Malaria Journal 2021 20:15, 6 January 2021

Although autochthonous malaria cases are no longer reported in Anhui Province, China, imported malaria has become a major health concern. The proportion of reported malaria cases caused by Plasmodium ovale spp. increased to levels higher than expected during 2012 to 2019, and showed two peaks, 19.69% in 2015 and 19.35% in 2018.

Low genetic diversity and strong immunogenicity within the apical membrane antigen-1 of Plasmodium ovale spp. imported from Africa to China

June 23, 2020 - 16:10 -- Open Access
Lei Y, Shen F, Cheng Y, et al.
Acta Trop. 2020 Jun 17:105591

Malaria is still an important challenge for global public health because of its extensive mortality and morbidity. Plasmodium ovale is mainly distributed in tropical regions of Africa and Asia. it includes two distinct ovale malaria species, which are P. ovale curtisi and P. ovale wallikeri. Apical membrane antigen-1 (AMA-1) is an asexual blood-stage protein which is essential for Plasmodium. Thus far, no study on gene polymorphism and immunogenicity of P. ovale AMA-1 (PoAMA-1) has been conducted. Amplified poama1 gene products from 14 P ovale curtisi samples and 12 P ovale wallikeri samples imported from Africa to Jiangsu Province, China were sequenced and their polymorphisms were analyzed.

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