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bone marrow; hypnozoite; malaria; Plasmodium; recrudescence; recurrence; relapse; spleen; vivax

Relapsing Malaria and Parasite Numbers

June 17, 2020 - 01:16 -- Miles Markus

Only a "few" hypnozoites occur in patients who have Plasmodium vivax infections, compared to the large, non-circulating merozoite biomass that is now known to be present.

Therefore, to readily ascribe P. vivax malarial recurrences to hypnozoite activation, as is currently common practice, is no longer appropriate without good reasons for doing so. Forget about what you were taught at university in this context and keep an open mind.

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