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pfhrp2/3

Uncovering hidden pfhrp2/3 deletion Plasmodium falciparum

June 10, 2020 - 15:08 -- Open Access
Author(s): 
Kobayashi T
Reference: 
EBioMedicine. 2020 Jun 5;56:102781

Deaths and transmission from malaria have declined significantly in the past decade, although the progress has somewhat stalled in recent years. Accurate and timely diagnosis is essential to providing adequate treatment to malaria cases. Plasmodium falciparum histidine-rich protein 2 (PfHRP2) based rapid diagnostic test (RDT) is widely used especially in Africa, where P. Falciparum accounts for 98%of estimated malaria cases. Despite its importance, reports of parasites lackingpfhrp2gene emerging across the globe are threatening the importance of this malaria diagnostic tool.

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