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Transcriptome analysis

NOT Open Access | Comparative transcriptome analysis of different stages of Plasmodium falciparum to explore vaccine and drug candidates

January 20, 2020 - 15:10 -- NOT Open Access
Guleria V, Jaiswal V
Genomics, Volume 112, Issue 1, January 2020, Pages 796-804

Malaria is a life-threatening disease causes huge burden on human health. Every year >200 million cases of malaria are reported globally. Researchers have carried out research on transcriptome of different stages of Plasmodium species to understand complex pathology of pathogens and to discover therapeutics. Researchers are targeting different stages of Plasmodium falciparum separately.

Transcriptome analysis of Plasmodium berghei during exo-erythrocytic development

September 30, 2019 - 13:40 -- Open Access
Reto Caldelari, Sunil Dogga, Marc W. Schmid, Blandine Franke-Fayard, Chris J. Janse, Dominique Soldati-Favre and Volker Heussler
Malaria Journal 2019 18:330, 24 September 2019

The complex life cycle of malaria parasites requires well-orchestrated stage specific gene expression. In the vertebrate host the parasites grow and multiply by schizogony in two different environments: within erythrocytes and within hepatocytes. Whereas erythrocytic parasites are well-studied in this respect, relatively little is known about the exo-erythrocytic stages.

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