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endemic burkitt lymphoma

Endemic Burkitt lymphoma: a complication of asymptomatic malaria in sub-Saharan Africa based on published literature and primary data from Uganda, Tanzania, and Kenya

July 28, 2020 - 14:42 -- Open Access
Author(s): 
Lawrence S. Redmond, Martin D. Ogwang, Sam M. Mbulaiteye, et al.
Reference: 
Malaria Journal 2020 19:239, 28 July 2020

Endemic Burkitt lymphoma (eBL) is an aggressive B cell non-Hodgkin lymphoma associated with antigenic stimulation from Plasmodium falciparum malaria. Whether eBL risk is related to malaria parasite density is unknown. To address this issue, children with eBL, asymptomatic and clinical malaria, as a surrogate of malaria parasite density, were assessed.

NOT Open Access | Mean platelet counts are relatively decreased with malaria but relatively increased with endemic Burkitt Lymphoma in Uganda, Tanzania, and Kenya

May 13, 2020 - 14:54 -- NOT Open Access
Author(s): 
Peprah S, Ogwang MD, Mbulaiteye SM, et al.
Reference: 
Br J Haematol. 2020 May 12

Platelet counts are decreased in Plasmodium falciparum malaria, which is aetiologically linked with endemic Burkitt lymphoma (eBL). However, the pattern of platelet counts in eBL cases is unknown. We studied platelet counts in 582 eBL cases and 2 248 controls enrolled in a case‐control study in Uganda, Tanzania and Kenya (2010–2016). Mean platelet counts in controls or eBL cases with or without malaria‐infection in controls versus eBLcases were compared using Student’s t‐test.

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