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chaperone-mediated protein

Directing Traffic: Chaperone-mediated protein transport in malaria parasites

May 13, 2020 - 14:00 -- Open Access
Florentin A, Cobb DW, Kudyba HM, Muralidharan V
Cell Microbiol. 2020 May 9:e13215

The ability of eukaryotic parasites from the phylum Apicomplexa to cause devastating diseases is predicated upon their ability to maintain faithful and precise protein trafficking mechanisms. Their parasitic life cycle depends on the trafficking of effector proteins to the infected host cell, transport of proteins to several critical organelles required for survival, as well as transport of parasite and host proteins to the digestive organelles to generate the building blocks for parasite growth.

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