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Influence of blood group, Glucose-6-phosphate dehydrogenase and Haemoglobin genotype on Falciparum malaria in children in Vihiga highland of Western Kenya

July 13, 2020 - 16:40 -- Open Access
Ahmed JS, Guyah B, Sang' D, Webale MK, Mufyongo NS, Munde E, Ouma C
BMC Infect Dis. 2020 Jul 9;20(1):487

Genetic diversity of ABO blood, glucose-6-phosphate dehydrogenase (G6PD) deficiency and haemoglobin type and their ability to protect against malaria vary geographically, ethnically and racially. No study has been carried out in populations resident in malaria regions in western Kenya.

G6PD and chloroquine: selecting the treatment against SARS-CoV-2

April 14, 2020 - 14:40 -- Open Access
Kassi EN, Papavassiliou KA, Papavassiliou AG
J Cell Mol Med. 2020 Apr 12

In light of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2 or COVID‐19) pandemic and the possible widespread use of chloroquine (a member of the drug class 4‐aminoquinoline primarily used to prevent and treat malaria and amebiasis) and its derivatives (e.g. hydroxychloroquine, a metabolite of chloroquine),1 a safety issue is addressed, concerning the selection of patients suitable to receive it.

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