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insecticide-resistant

Behavioral response of insecticide-resistant mosquitoes against spatial repellent: A modified self-propelled particle model simulation

January 1, 2021 - 16:06 -- Open Access
Author(s): 
Zhou G, Yu L, Wang X, Zhong D, Lee MC, Kibret S, Yan G
Reference: 
PLoS One. 2020 Dec 29;15(12):e0244447

Rapidly increasing pyrethroid insecticide resistance and changes in vector biting and resting behavior pose serious challenges in malaria control. Mosquito repellents, especially spatial repellents, have received much attention from industry. We attempted to simulate interactions between mosquitoes and repellents using a machine learning method, the Self-Propelled Particle (SPP) model, which we modified to include attractiveness/repellency effects. We simulated a random walk scenario and scenarios with insecticide susceptible/resistant mosquitoes against repellent alone and against repellent plus attractant (to mimic a human host).

A steroid hormone agonist reduces female fitness in insecticide-resistant Anopheles populations

April 13, 2020 - 15:21 -- Open Access
Author(s): 
Brown F, Paton DG, Catteruccia F, Ranson H, Ingham VA
Reference: 
Insect Biochem Mol Biol. 2020 Apr 7:103372

Insecticide based vector control tools such as insecticide treated bednets and indoor residual spraying represent the cornerstones of malaria control programs. Resistance to chemistries used in these programs is now widespread and represents a significant threat to the gains seen in reducing malaria-related morbidity and mortality.

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