In malaria-endemic countries, malaria during pregnancy is associated with adverse birth outcomes, including low birth weight (i.e., <2.5 kg). However, the effects of the widely promoted and recommended approaches of intermittent preventive treatment for malaria in pregnancy and insecticide-treated nets for pregnant women on low birth weight have been insufficiently examined. This analysis investigates the independent and combined effects of intermittent preventive treatment for malaria in pregnancy and insecticide-treated nets on low birth weight among Malawian children.
low birth weight
While there is increasing evidence on the safety of artemisinin-based combination therapy (ACT) for the case management of malaria in early pregnancy, little is known about the association between exposure to ACT during the first trimester and the effect on fetal growth.