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ABO blood group

Not Open Access | ABO blood group should be considered and reported when red blood cell exchange transfusion is used to treat Plasmodium falciparum Malaria patients

September 2, 2020 - 08:28 -- NOT Open Access
Author(s): 
Ryan Philip Jajosky, Audrey N.Jajosky, Philip G.Jajosky
Reference: 
Transfusion Clinique et Biologique, Volume 27, Issue 3, August 2020, Pages 179-184

Laboratory and epidemiologic studies have clarified how persons born with malaria-resistant red blood cells (RBCs)–like group-O, sickle-trait, and C-trait RBCs–are protected against death or severe disease due to Plasmodium falciparum (Pf) infection. Compared to malaria-promoting RBCs–like non-O or hemoglobin-AA RBCs–inborn RBC protection against severe Pf malaria can be profound: up to 10-fold greater.

NOT Open Access | Effects of IgG and IgM autoantibodies on non-infected erythrocytes is related to ABO blood group in Plasmodium vivax malaria and is associated with anemia

March 2, 2020 - 15:27 -- NOT Open Access
Author(s): 
Mourão LC, Medeiros CMP, Braga ÉM, et al.
Reference: 
Microbes Infect. 2020 Feb 22. pii: S1286-4579(20)30031-9

Autoantibodies play an important role in the destruction of non-infected red blood cells (nRBCs) during malaria. However, the relationship between this clearance and ABO blood groups is yet to be fully enlightened, especially for Plasmodium vivax infections. Here we show that anti-RBC IgG and IgM are increased in anemic patients with acute vivax malaria.

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