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NOT Open Access | IgG antibody response against Plasmodium falciparum Aminopeptidase 1 antigen in Gabonese children living in Makokou and Franceville

February 16, 2020 - 09:20 -- NOT Open Access
Lydie Oyegue-Liabagui S, Imboumy-Limoukou RK, Kouna CL, Bangueboussa F, Schmitt M, Florent I, Bernard Lekana-Douki J
Clin Exp Immunol. 2020 Feb 6

The search for novel chemical classes of anti‐malarial compounds to cope with the current state of chemoresistance of malaria parasites, led to the identification of PfA‐M1 as a new therapeutic target. PfA‐M1, known to be involved in the hemoglobin digestion cascade which helps to provide most of the amino acids necessary to the parasite’s metabolism, is currently considered as a promising target for anti‐malarial chemotherapy.

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