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anopheles vestitipennis

Development of molecular assays to detect target-site mechanisms associated with insecticide resistance in malaria vectors from Latin America

June 24, 2019 - 15:51 -- Open Access
Author(s): 
Juan C. Lol, David Castañeda, Lucy Mackenzie-Impoinvil, Carla G. Romero, Audrey Lenhart and Norma R. Padilla
Reference: 
Malaria Journal 2019 18:202, 20 June 2019

Malaria remains an important public health problem in Latin America, and the development of insecticide resistance in malaria vectors poses a major threat to malaria elimination efforts. Monitoring of insecticide susceptibility and the determination of the mechanisms involved in insecticide resistance are needed to effectively guide the deployment of appropriate vector control measures. Here, molecular assays have been developed to screen for mutations associated with insecticide resistance on the voltage-gated sodium channel (VGSC) and acetylcholinesterase-1 (Ace-1) genes in four malaria vectors from Latin America.

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