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therapies

NOT Open Access | Desperately Seeking Therapies for Cerebral Malaria

January 20, 2020 - 16:28 -- NOT Open Access
Author(s): 
Riggle BA, Miller LH, Pierce SK
Reference: 
J Immunol January 15, 2020, 204 (2) 327-334

Malaria is a deadly infectious disease caused by parasites of the Plasmodium spp. that takes an estimated 435,000 lives each year, primarily among young African children. For most children, malaria is a febrile illness that resolves with time, but in ∼1% of cases, for reasons we do not understand, malaria becomes severe and life threatening. Cerebral malaria (CM) is the most common form of severe malaria, accounting for the vast majority of childhood deaths from malaria despite highly effective antiparasite chemotherapy.

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