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insecticides

Self-limiting paratransgenesis

August 19, 2020 - 16:01 -- Open Access
Author(s): 
Huang W, Wang S, Jacobs-Lorena M
Reference: 
PLoS Negl Trop Dis. 2020 Aug 18;14(8):e0008542

Presently, the principal tools to combat malaria are restricted to killing the parasite in infected people and killing the mosquito vector to thwart transmission. While successful, these approaches are losing effectiveness in view of parasite resistance to drugs and mosquito resistance to insecticides. Clearly, new approaches to fight this deadly disease need to be developed.

Resistance status of Anopheles gambiae (s.l.) to four commonly used insecticides for malaria vector control in South-East Nigeria

March 30, 2020 - 10:02 -- Open Access
Author(s): 
Chukwuekezie O, Nwosu E, Gnanguenon V, et al.
Reference: 
Parasit Vectors. 2020 Mar 24;13(1):152.

Progress made in the control of malaria vectors globally is largely due to the use of insecticides. However, success in the fight against malaria has slowed down or even stalled due to a host of factors including insecticide resistance. The greatest burden of the disease is felt in Africa, particularly Nigeria. Unfortunately, adequate information on insecticide resistance is lacking in many parts of the country, particularly the South-East Zone. Hence, this study aims to bridge the information gap in the Zone.

Use of Insecticides in Agriculture and the Prevention of Vector-Borne Diseases: Population Knowledge, Attitudes, Practices and Beliefs in Elibou, South Côte d'Ivoire

March 9, 2020 - 14:17 -- Open Access
Author(s): 
N'Dri BP, Heitz-Tokpa K, Chouaïbou M, Raso G, Koffi AJ, Coulibaly JT, Yapi RB, Müller P, Utzinger J
Reference: 
Trop Med Infect Dis. 2020 Mar 1; 5(1). pii: E36

People’s knowledge, attitudes, practices and beliefs (KAPB) pertaining to malaria are generally well described. However, little is known about population knowledge and awareness of insecticide resistance in malaria vectors. The aim of this study was to investigate KAPB related to insecticide resistance in malaria vectors due to the use of insecticides in agriculture and the prevention against mosquitoes. In mid-2017, we carried out a cross-sectional survey in Elibou, South Côte d’Ivoire, employing a mixed methods approach.

Taking the ‘I’ out of LLINs: using insecticides in vector control tools other than long-lasting nets to fight malaria

February 22, 2020 - 16:25 -- Open Access
Author(s): 
Krijn P. Paaijmans and Silvie Huijben
Reference: 
Malaria Journal 2020 19:73, 14 February 2020

Long-lasting insecticidal nets, or LLINs, have significantly reduced malaria morbidity and mortality over the past two decades. The net provides a physical barrier that decreases human-mosquito contact and the impregnated insecticide kills susceptible mosquito vectors upon contact and may repel them. However, the future of LLINs is threatened as resistance to pyrethroids is now widespread, the chemical arsenal for LLINs is very limited, time from discovery of next-generation insecticides to market is long, and persistent transmission is frequently caused by vector populations avoiding contact with LLINs.

Resistance status of Anopheles gambiae s.l. to insecticides following the 2011 mass distribution campaign of long-lasting insecticidal nets (LLINs) in the Plateau Department, south-eastern Benin

January 20, 2020 - 15:50 -- Open Access
Author(s): 
Arthur Sovi, Renaud Govoétchan, Martin Codjo Akogbeto, et al.
Reference: 
Malaria Journal 2020 19:26, 15 January 2020

In 2011, Benin’s National Malaria Control Programme (NMCP) organized a nationwide mass distribution campaign of LLINs throughout the country. Following this intervention, it was important to assess whether the level of susceptibility of malaria vectors to insecticides had remained the same as compared to the pre-intervention period. The current study investigated this.

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