The world's scientific and social network for malaria professionals
Subscribe to free Newsletter | 10366 malaria professionals are enjoying the free benefits of MalariaWorld today

G6PD A- allele

Evidence of positively selected G6PD A- allele reduces risk of Plasmodium falciparum infection in African population on Bioko Island

January 15, 2020 - 09:10 -- Open Access
Author(s): 
Liang XY, Chen JT, Ma YB, Huang HY, Xie DD, Monte-Nguba SM, Ehapo CS, Eyi UM, Zheng YZ, Liu XZ, Zha GC, Lin LY, Chen WZ, Zhou X, Lin M
Reference: 
Mol Genet Genomic Med. 2019 Dec 24:e1061

Glucose‐6‐phosphate dehydrogenase (G6PD) is an essential enzyme that protects red blood cells from oxidative damage. Although G6PD‐deficient alleles appear to confer a protective effect of malaria, the link with clinical protection against Plasmodium infection is conflicting.

Subscribe to RSS - G6PD A- allele