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MTIP

Polarization of MTIP is a signature of gliding locomotion in Plasmodium ookinetes and sporozoites

January 15, 2020 - 09:07 -- Open Access
Author(s): 
Siden-Kiamos I, Goosmann C, Buscaglia CA, Brinkmann V, Matuschewski K, Montagna GN
Reference: 
Molecular and Biochemical Parasitology, Volume 235, January 2020, 111247

Gliding motility and cell invasion are essential for the successful transmission of Plasmodium parasites. These processes rely on an acto-myosin motor located underneath the parasite plasma membrane. The Myosin A-tail interacting protein (MTIP) connects the class XIV myosin A (MyoA) to the gliding-associated proteins and is essential for assembly of the motor at the inner membrane complex.

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