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signaling pathway

NOT Open Access | Dihydroartemisinin inhibits endothelial cell tube formation by suppression of the STAT3 signaling pathway

January 15, 2020 - 08:01 -- NOT Open Access
Gao P, Wang LL, Liu J, Dong F, Song W, Liao L, Wang B, Zhang W, Zhou X, Xie Q, Sun R, Liu J
Life Sciences, Volume 242, 1 February 2020, 117221

Endothelial cell (EC) tube formation is crucial for tumor angiogenesis, which becomes a target for chemotherapy. The anti-malaria agent dihydroartemisinin (DHA) inhibited tumor growth and angiogenesis. The aim of this study was to investigate the effects of DHA on EC tube formation and the underlying mechanisms.

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