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Genetic characterization of Plasmodium vivax isolates from Pakistan using circumsporozoite protein (pvcsp) and merozoite surface protein-1 (pvmsp-1) genes as genetic markers

March 3, 2021 - 15:26 -- Open Access
Zainab Bibi, Anam Fatima, Rehana Rani, Ayesha Maqbool, Samea Khan, Shumaila Naz and Shahid Waseem
Malaria Journal 2021 20:112, 25 February 2021

Plasmodium vivax contributes to over 70% malaria burden in Pakistan, but limited data exists on various aspects including genetic diversity of the parasite as compared to other parts of the world. Since the information about the genetic diversity of P. vivax assists to understand the population dynamics of the parasite, the current study was designed to understand population divergence of P. vivax in Pakistan using circumsporozoite protein (pvcsp) and merozoite surface protein-1 (pvmsp-1) genes as molecular markers.

Effectiveness of a health education intervention on the use of long-lasting insecticidal nets for the prevention of malaria in pregnant women of Pakistan: a quasi-experimental study

June 30, 2020 - 14:26 -- Open Access
Ramesh Kumar, Midhat Farzeen, Assad Hafeez, Baseer Khan Achakzai, Muskan Vankwani, Manohar Lal, Rabia Iqbal and Ratana Somrongthong
Malaria Journal 2020 19:232, 29 June 2020

About one quarter of pregnant women in the population of Pakistan are using long-lasting insecticide-treated bed nets (LLINs) for prevention of malaria. Past research reported that adequate information and education would act as mediator to change behaviour among patients for prevention of malaria infection. The effective use of LLINs would contribute to reduction of disease burden caused by malaria. The aim of this study was to determine the effectiveness of health education on the adoption of LLINs among pregnant women living in Tharparkar, a remote district in Sindh Province, Pakistan.

Surveillance of genetic markers associated with Plasmodium falciparum resistance to artemisinin-based combination therapy in Pakistan, 2018–2019

June 9, 2020 - 16:16 -- Open Access
Abdul Qader Khan, Leyre Pernaute-Lau, Aamer Ali Khattak, Sanna Luijcx, Berit Aydin-Schmidt, Mubashir Hussain, Taj Ali Khan, Farees Uddin Mufti and Ulrika Morris
Malaria Journal 2020 19:206, 8 June 2020

The spread of artemisinin resistance in the Greater Mekong Subregion of Southeast Asia poses a significant threat for current anti-malarial treatment guidelines globally. The aim of this study was to assess the current prevalence of molecular markers of drug resistance in Plasmodium falciparum in the four provinces with the highest malaria burden in Pakistan, after introducing artemether–lumefantrine as first-line treatment in 2017.

Correction to: Occurrence and seasonal variation of human Plasmodium infection in Punjab Province, Pakistan

January 14, 2020 - 10:21 -- Open Access
Qureshi NA, Fatima H, Afzal M, Khattak AA, Nawaz MA
BMC Infect Dis. 2020 Jan 8; 20(1):25

After publication of the original article [1], we were notified that an author’s name has been erroneously spelled. Aamir Ali Khattak should be replaced with Aamer Ali Khattak.

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