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Evaluating Vertical Malaria Community Health Worker Programs as Malaria Declines: Learning From Program Evaluations in Honduras and Lao PDR

March 17, 2021 - 17:23 -- Open Access
Napier HG, Baird M, Cohen JM, et al.
Glob Health Sci Pract. 2021 Mar 16;9(Suppl 1):S98-S110

Across the Greater Mekong Subregion (GMS) and Central America, governments commonly employ community health workers (CHWs) to improve access to and uptake of malaria services. Many of these networks are vertical in design, organized to extend malaria-only services to those remaining communities in which malaria persists.

Spatio-temporal associations between deforestation and malaria incidence in Lao PDR

March 13, 2021 - 16:33 -- Open Access
Rerolle F, Dantzer E, Lover AA, Marshall JM, Hongvanthong B, Sturrock HJ, Bennett A
Elife. 2021 Mar 9;10:e56974

As countries in the Greater Mekong Sub-region (GMS) increasingly focus their malaria control and elimination efforts on reducing forest-related transmission, greater understanding of the relationship between deforestation and malaria incidence will be essential for programs to assess and meet their 2030 elimination goals. Leveraging village-level health facility surveillance data and forest cover data in a spatio-temporal modeling framework, we found evidence that deforestation is associated with short-term increases, but long-term decreases in confirmed malaria case incidence in Lao People's Democratic Republic (Lao PDR).

New insights into malaria vector bionomics in Lao PDR: a nationwide entomology survey

November 10, 2020 - 14:00 -- Open Access
Sébastien Marcombe, Santi Maithaviphet, Julie Bobichon, Nothasin Phommavan, Simone Nambanya, Vincent Corbel and Paul T. Brey
Malaria Journal 2020 19:396, 9 November 2020

In Laos, the malaria burden remains high despite a significant reduction of cases during the last decade. In the context of the disease elimination by 2030, a nationwide entomological survey was conducted to better understand the distribution, abundance and behaviour of major malaria vectors (Anopheles spp.) in the country.

The use of ultrasensitive quantitative-PCR to assess the impact of primaquine on asymptomatic relapse of Plasmodium vivax infections: a randomized, controlled trial in Lao PDR

January 7, 2020 - 14:55 -- Open Access
Koukeo Phommasone, Frank van Leth, Mayfong Mayxay, et al.
Malaria Journal 2020 19:4, 3 January 2020

Trials to assess the efficacy of the radical cure of Plasmodium vivax malaria with 8-aminoquinolines require that most post-treatment relapses are identified, but there is no consensus on the optimal duration of follow-up in either symptomatic or asymptomatic vivax malaria. The efficacy of a 14-day course of primaquine on the cumulative incidence of recurrent asymptomatic P. vivax infections detected by ultrasensitive quantitative PCR (uPCR) as a primary endpoint was assessed.

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